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зачинатель
poslabšanje
ag·gra·va·tion [ˌægrəˈveɪʃən] СУЩ. no мн.
1. aggravation (worsening):
aggravation
2. aggravation разг. (annoyance):
aggravation
PONS OpenDict

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Одноязычные примеры (не проверены редакцией PONS)
Cold also causes aggravation of symptoms and can initiate a relapse.
en.wikipedia.org
A short course of proton pump inhibitor therapy may decrease aggravation by stomach acid reflux into the esophagus.
en.wikipedia.org
The promotion ceased running regular shows and events in 2001 due to management aggravation.
en.wikipedia.org
Many property owners want to sell their real estate, but do not want the aggravation associated with showing the property.
en.wikipedia.org
Likewise, they are avoided in order to prevent the onset or aggravation of adenomyosis.
en.wikipedia.org