Frequent subsequent waves of the plague continued to strike throughout the 6th, 7th and 8th centuries, with the disease becoming more localized and less virulent.
Additionally, it is noted that evidence with other pathogens suggests that pathogens that emerge from amoeba are more resistant to antibiotics and more virulent.
Since the proteins from the different sample types (e.g. healthy/diseased, virulent/non-virulent) are run on the same gel they can be directly compared.
