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irreversibly
irréversiblement
irreversibly [брит. ɪrɪˈvəːsɪbli, америк. ˈˌɪ(r)rəˈvərsəbli] НАРЕЧ.
irreversibly
PONS OpenDict

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Одноязычные примеры (не проверены редакцией PONS)
And that selfishness is what has gotten us into the terrible quagmire in which the world is sinking, almost irreversibly, unless something big happens.
en.wikipedia.org
To her surgeons disbelief, her pain ceased, she started walking, and three irreversibly gangrenous toes spontaneously sloughed.
en.wikipedia.org
We could perform an observation, which irreversibly collapses the system into some eigenstate of an observable, corrupting the information contained in the qubit(s).
en.wikipedia.org
It works by interfering with the transmission of nerve impulses in insects by binding irreversibly to specific insect nicotinic acetylcholine receptors.
en.wikipedia.org
Faults such as these damaged the tape irreversibly, a particular problem with irreplaceable tapes filmed by users.
en.wikipedia.org