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The Sabin vaccine worked in the intestines to block the poliovirus from entering the bloodstream.
en.wikipedia.org The Sabin vaccine is given orally, replicates in the intestines of vaccines, induces both mucosal and systemic immunity, and protects against infection of the intestine by ingested virulent poliovirus.
en.wikipedia.org The problem with the Sabin vaccine is that the weakened virus can revert back to a dangerous form in some people.
www.theatlantic.com The attenuated poliovirus in the Sabin vaccine replicates very efficiently in the gut, the primary site of infection and replication, but is unable to replicate efficiently within nervous system tissue.
en.wikipedia.org An oral vaccine, the Sabin vaccine consists of weakened forms of the viruses that cause polio.
en.wikipedia.org